First line:

1. Epinephrine 0.01 mg/kg (use 1:1000 sol) q5-15min IM (max dose 0.3 mg in kids or 0.5 mg in adults)

1. Methylprednisolone (Solumedrol) 1-2mg/kg/day IV (all ages) (usual dose is 125mg IV for most adults)

1. Benadryl 50 mg IV/IM/po q6h (kids: 5 mg/kg/day, q6-8h, max 300 mg/day)

Alternatives/Adjuncts:

• Prednisone 0.5-1mg/kg/day
• Ranitidine (Zantac) 50 mg IV q6h (if <16 yo use 4mg/kg/day divided q8h)

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The Compendium platform was created by David Kwinter, MD, CCFP(EM).