Pathophysiology
     Interventricular septal hypertrophy
Hx
     More common in African Americans
     Autosomal dominant inheritance
Sx
     Syncope (possibly multifactorial)
          May be due to
               Outflow obstruction
               Arrhythmia
               Ischemia
               Ventricular baroreceptor response that inappropriately causes vasodilation
     Dyspnea
     Chest pain
PE
     Carotid pulse with dual upstroke occurs from midsystolic obstruction that develops as the heart contracts
     Crescendo-decrescendo systolic murmur along the L sternal border with strong apical impulse without carotid radiation
          Valsalva enhances the murmur as preload decreases since this lessens the size of the ventricular cavity and causes increase outflow obstruction

Content on this page has not been checked for accuracy. The author's credentials have not been confirmed. Always use multiple peer-reviewed scholarly sources and good clinical judgement in your decision making.

The Compendium platform was created by David Kwinter, MD, CCFP(EM).

Dr. Kwinter is a Cayman Family Doctor. He runs a Family Medicine Clinic at Cayman Medical in George Town, Grand Cayman, Cayman Islands.