A BDZ, the #1 prescribed mental health drug
Mechanism
Binds GABA-alpha receptors
Enhances the affinity of GABA for the receptor, allows increased opening of the GABA-alpha channel
Indications
Anxiety
Panic disorder (first-line)
Indications, off label
Phobias
Peroperative anxiety
A/E
Do NOT use with alcohol
Long-term use can lead to tolerance, withdrawal
Special caution with elderly
Notes
Half-life is 12 hours
High abuse potential