MEN-1 | MEN-2a | MEN-2b |
Defect in tumor suppressor gene called Menin | ||
Pituitary adenoma | ||
Pancreatic endocrine tumor | ||
Parathyroid hyperplasia | Parathyroid hyperplasia | |
Medullary thyroid cancer (calcitonin-secreting) virtually 100% of pts | Medullary thyroid cancer (calcitonin-secreting) | |
Pheochromocytoma | Pheochromocytoma | |
Mucosal neuromas; Marfanoid habitus |