Serotonin antagonist and reuptake inhibitor (SARI)
     Antagonizes alpha-1 adrenergic AND
     Antagonizes serotonin 5-HT2A/C receptors
See also:
     Depression and Anxiety Formulary
Indications
     MDD
     Insomnia
     Sleep disturbances
Adverse effects
     Priapism
Notes
     Fewer prominent anticholinergic effects (dry mouth, constipation, tachycardia)
     Fewer sexual side-effects
     Desirable side-effect profile
     Multiple uses
Cost
     Cheap

Content on this page has not been checked for accuracy. The author's credentials have not been confirmed. Always use multiple peer-reviewed scholarly sources and good clinical judgement in your decision making.

The Compendium platform was created by David Kwinter, MD, CCFP(EM).

Dr. Kwinter is a Cayman Family Doctor. He runs a Family Medicine Clinic at Cayman Medical in George Town, Grand Cayman, Cayman Islands.