Serotonin antagonist and reuptake inhibitor (SARI)
Antagonizes alpha-1 adrenergic AND
Antagonizes serotonin 5-HT2A/C receptors
See also:
Depression and Anxiety Formulary
Indications
MDD
Insomnia
Sleep disturbances
Adverse effects
Priapism
Notes
Fewer prominent anticholinergic effects (dry mouth, constipation, tachycardia)
Fewer sexual side-effects
Desirable side-effect profile
Multiple uses
Cost
Cheap