Sx
     Uncontrolled HTN
     Increase in ring size/hand size/feet size
     Sweaty hands/increased oiliness of skin

     Headaches

     Visual changes

     Visual field deficits
     Skin tags
     Capal tunnel syndrome

Workup

     Free testosterone

     PRL

     TSH

     Fasting glucose tolerance test showing suppression of GH and IGF-1

Dx
     The most specific test/gold standard:
          Measure GH levels following an oral glucose load
          Give 75 g of oral glucose and most normal individuals will suppress serum GH levels to below 1 mcg/dL, whereas patients with acromegaly are unable to suppress or sometimes paradoxically increase serum GH levels

 

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The Compendium platform was created by David Kwinter, MD, CCFP(EM).