See also:
Pneumonia
Fever in a child less than 30 days old
Fever in a child 30-90 days old
Fever in a child greater than 90 days old
Epidemiology
Epidemics occur in the winter months and may cause up to 40,000 deaths annually in the US
Elderly people make up more than 90% of the fatalities
Hx
Abrupt onset of sx
Sx
URI and LRI symptoms plus systemic effects
Fever
Chills
Malaise
Myalgias
Cough
Coryza
PE
Febrile
Wheezes, crackles and coarse breath sounds
Labs
Leukopenia is common
Proteinuria may be present
CXR
May be normal
May show interstitial or alveolar pattern
Dx
Nasal swabs for influenza antigens are the fastest way to confirm dx
Tx
Antiviral tx must be started within 48 hours to be effective
Oseltamivir and Zanamivir are neuraminidase inhibitors, which are the newest therapies
Rimantadine and Amatadine are other options, but are only effective against influenza A